Brugia timori is a helminth/filarial nematode

Disease / Pathology

Brugia timori periodicity is nocturnal. It is the cause of Timor Filariasis which causes an acute fever and chronic lymphedema. The acute phase of the disease has an eosinophilia component to it.

Location in the Host

Brugia timori adults are located in the lymphatics while the microfilariae are found in the peripheral blood.

Geographic Distribution

Brugia timori is found in the Islands of Timor & Lesser Sunda in Indonesia.

Life Cycle

The nematode is transmitted via the bite of the Anopheles mosquito, which in areas where it is endemic, breeding of the mosquitos occurs in the rice fields found there.

Morphology & Diagnosis

Brugia timori microfilariae are 290-325um in length and have a sheath that tapers gradually. It is nearly invisible and when stained with Geimsa stain, the stain that is taken up it does not stain pink as with B. malayi and W. bancrofti. Nuclei extend to tip of tail, are subterminal and terminal, no tail constriction between two terminal nuclei which are elongate to oval in shape.

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